Benzonitrile, 4-[1-[(2S)-2-aminopropyl]-1H-pyrazol-3-yl]-2-chloro- - Names and Identifiers
Benzonitrile, 4-[1-[(2S)-2-aminopropyl]-1H-pyrazol-3-yl]-2-chloro- - Physico-chemical Properties
Molecular Formula | C13H13ClN4
|
Molar Mass | 260.72 |
Density | 1.28±0.1 g/cm3(Predicted) |
Boling Point | 450.0±45.0 °C(Predicted) |
pKa | 8.82±0.10(Predicted) |
Benzonitrile, 4-[1-[(2S)-2-aminopropyl]-1H-pyrazol-3-yl]-2-chloro- - Upstream Downstream Industry
Benzonitrile, 4-[1-[(2S)-2-aminopropyl]-1H-pyrazol-3-yl]-2-chloro- - Introduction
(S)-4-(1-(2-aminopropyl)-1H-pyrazol-3-yl)-2-chlorobenzonitrile, also known as (S)-4-(1-(2-aminopropyl)-1H-pyrazol-3-yl)-2-chlorobenzonitrile, it is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White crystalline solid
-Molecular formula: C15H14ClN5
-Molecular weight: 297.76g/mol
-Melting point: 172-174 degrees Celsius
-Solubility: Soluble in chloroform, dichloromethane and ethanol, insoluble in water.
Use:
- (S)-4-(1-(2-aminopropyl)-1H-pyrazol-3-yl)-2-chlorobenzonitrile is a cholesteryl ester transfer protein (CETP) inhibitor.
-It can be used to study the biological processes related to cholesterol metabolism and cholesterol transport.
Method:
There are many ways to prepare (S)-4-(1-(2-aminoppyl)-1H-pyrazol-3-yl)-2-chlorobenzonitrile, one of which is common as follows:
-First, 2-chlorobenzonitrile and (S)-2-amino-1-propanol are reacted to form a transition compound.
-Then, the transition compound is reacted with (S)-4-3-(1H-pyrazol-3-yl) pyrrolcyclopentadiene to produce the target product.
Safety Information:
(S)-4-(1-(2-aminopropyl)-1H-pyrazol-3-yl)-2-chlorobenzonitrile is a toxic substance, you need to pay attention to the following matters when using:
-Avoid contact with skin and eyes. Wear protective gloves, goggles and protective clothing when using.
-Use in a well-ventilated place to avoid inhaling aerosols or dust.
-Storage should be separated from flammable substances and oxidants to avoid sources of fire.
-In the event of inhalation, ingestion or skin contact, immediately take appropriate first aid measures and seek medical advice.
Last Update:2024-04-10 22:29:15